Integrin Beta4 Polyclonal Antibody, 50ul[BT-AP04591] Culture Tubes Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding different isoforms are described for this gene

These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes

The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane

The protein encoded by this gene is a member of kinesin-like protein family

The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription

Integrin Beta4 Polyclonal Antibody, 50ul[BT-AP04591] Culture Tubes Two alternatively spliced transcript variantsIntegrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand binding specificities. Integrins mediate cell matrix or cell cell adhesion, and transduced signals that regulate gene expression and cell growth. ITGB4 encodes Integrin beta 4, a receptor for the laminins. This subunit