IL-2R Beta Polyclonal Antibody, 50ul[BT-AP04489] Peptide Modification Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been found for CHEK1

optic nerve atrophy

which encodes a fusion protein comprised of sequence sharing identity with each individual gene product

and are postulated to function as brain-specific chemokines or neurokines

Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome

IL-2R Beta Polyclonal Antibody, 50ul[BT-AP04489] Peptide Modification Several alternatively spliced transcript variantsThe interleukin 2 receptor, which is involved in T cell mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha beta subunit heterodimer, while the high affinity form consists of an alpha beta gamma subunit heterotrimer. Both the intermediate and high affinity