AZD-5438 Size:Solid 2 mg [3] Bepotastine (100 μM) dose-dependently

[3] Bepotastine (100 μM) dose-dependently inhibits chemotaxis of cultured guinea pig peritoneal eosinophils induced by LTB4

a novel and potent p21-activated kinase 4 inhibitor

FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) extracted from patent WO 2012064642 A1

which is an angiotensin converting enzyme (ACE) inhibitor

the major inhibitory neurotransmitter in the central nervous system by blocking the GABA transporter and hence is classified as a GABA reuptake inhibitor

AZD-5438 Size:Solid 2 mg [3] Bepotastine (100 μM) dose-dependentlyAZD5438 is a potent inhibitor of cyclin dependent kinase (cdk) 1, 2, and 9 (IC(50), 16, 6, and 20 nmol L, respectively). In vitro, AZD5438 showed significant antiproliferative activity in human tumor cell lines (IC(50) range, 0. 2 1. 7 micromol L), causing inhibition of the phosphorylation of cdk substrates pRb, nucleolin, protein phosphatase 1a, and RNA polymerase II COOH terminal domain and blocking cell cycling at G(2) M, S, and G(1) phases.