PIK-294 - CAS# 900185-02-6 0097 573:118842

573:118842

and PAX6 protein expression

is a widely used γ-secretase inhibitor and serves as an inhibitor of Notch

Ca/c2*1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19

but results from the study indicate that KY02111 might function downstream from GSK3b and APC in b-catenin destruction complex

PIK-294 - CAS# 900185-02-6 0097 573:118842PIK 294, CAS No. 900185 02 6, is a highly selective inihibitor of the phosphoinositide 3 kinase (PI3K) p110 with an IC50 value of 10 nM compared to IC50 values of 10 M, 490 nM and 160 nM for PI3K , respectively. PIK 294 has been used to help distinguish the unique roles of the various PI3 K isoforms. PIK 294 inhibited both chemokinetic and chemotactic CXCL8 induced migration. Product information CAS Number: 900185 02 6 Molecular Weight: 489. 53