Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 TAE684 inhibits STAT3 and STAT5

TAE684 inhibits STAT3 and STAT5 phosphorylation in a dose-dependent manner in both Ba/F3 NPM-ALK and Karpas-299 cells

Chemical Name: 2-hydroxy-4-(2-(tosyloxy)acetamido)benzoic acid

InChiKey: VNDWQCSOSCCWIP-UHFFFAOYSA-N

PAI-039 is a small-molecule inhibitor of PAI-1 activity

5 mM) Water: <1 mg/mL

Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 TAE684 inhibits STAT3 and STAT5Su 11274, CAS No. 658084 23 2, is a selective Met tyrosine kinase inhibitor with IC50 of 10 nM. Su 11274 increases tumorigenicity and enriched for melanoma initiating cells by bioenergetic modulation. Su 11274 suppresses proliferation and motility of pancreatic cancer cells. Su 11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation. Su 11274 exhibits a selective inhibition pattern toward different receptor mutated