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AC220 - CAS# 950769-58-1 Catalog No.:M60435-2S mice) treatment demonstrates antitumor activity

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AC220 - CAS# 950769-58-1 Catalog No.:M60435-2S mice) treatment demonstrates antitumor activityQuizartinib, also know as AC220 and AC010220, CAS No. 950769 58 1, is an orally available FLT3 STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS related tyrosine kinase 3 (FLT3 STK1), colony stimulating factor 1 receptor (CSF1R FMS), stem cell factor receptor (SCFR KIT), and platelet derived growth factor receptors (PDGFRs),

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Description

mice) treatment demonstrates antitumor activity in HCC xenograft models

5 mg/kg dissolved in 0

SAG was shown to prevent glucocorticoid-induced neonatal cerebellar injury

InChi: InChI=1S/C16H19Cl2N5

Smiles: COC1=CC2=C(NCCCCCN3CCCC3)N=C(N=C2C=C1OC)N1CCCC1

AC220 - CAS# 950769-58-1 Catalog No.:M60435-2S mice) treatment demonstrates antitumor activityQuizartinib, also know as AC220 and AC010220, CAS No. 950769 58 1, is an orally available FLT3 STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS related tyrosine kinase 3 (FLT3 STK1), colony stimulating factor 1 receptor (CSF1R FMS), stem cell factor receptor (SCFR KIT), and platelet derived growth factor receptors (PDGFRs),

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