CERC-501 - CAS# 1174130-61-0 size:10mg solid resulting in accumulation of polyubiquitin

resulting in accumulation of polyubiquitin

as well as SHP protein level in primary hepatocytes

InChiKey: MVOZLTFXYGHZPM-UHFFFAOYSA-N

Samaniego F

AZD-2281 (Olaparib) is a single digit nanomolar inhibitor of both PARP-1 and PARP-2 that shows standalone activity against BRCA1-deficient breast cancer cell lines

CERC-501 - CAS# 1174130-61-0 size:10mg solid resulting in accumulation of polyubiquitinCERC 501, also known as JNJ 67953964, LY 2456302 and Aticaprant, CAS No. 1174130 61 0, is a potent, selective, short acting antagonist of the opioid receptor (KOR) (Ki = 0. 81 nM vs. 24. 0 nM and 155 nM for the opioid receptor (MOR) and opioid receptor (DOR). Aticaprant is under development for the treatment of major depressive disorder and substance use disorders including alcoholism, nicotine addiction, and illicit drug dependence. Aticaprant has