MDV-3100 - CAS# 915087-33-1 60135 Pizarro JG

Pizarro JG

) significantly delays in lymphoma development and shows 100- to 1

918633-87-1

is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM)

Targeting the multiple myeloma hypoxic niche with TH-302

MDV-3100 - CAS# 915087-33-1 60135 Pizarro JGEnzalutamide, also known as MDV3100, CAS No. 915087 33 1, is an orally bioavailable, organic, non steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation