ELR510444 - CAS# 1233948-35-0 size:10mg solid InChiKey: QQAHYSZVJLHCNA-UHFFFAOYSA-N

InChiKey: QQAHYSZVJLHCNA-UHFFFAOYSA-N

The circadian expression pattern of an array of metabolic genes in the liver

InChi: InChI=1S/C16H16N4O

Su-11274 inhibits cell viability in c-Met-expressing non-small cell lung cancer (NSCLC) cells with IC50 values of 0

DeLucas LJ

ELR510444 - CAS# 1233948-35-0 size:10mg solid InChiKey: QQAHYSZVJLHCNA-UHFFFAOYSA-NELR510444, CAS No. 1233948 35 0, is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30. 9 nM in MDA MB 231 cells, inhibited the rate and extent of purified tubulin