BMS-911543 - CAS# 1271022-90-2 Size:Solid 10 mg Identification and characterization of small

Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor

It is of the nucleoside analog reverse transcriptase inhibitor (NRTI) class

Ergoloid Mesylates binds to the GABAA receptor Cl- channel

InChi: InChI=1S/C19H20N4O

6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1

BMS-911543 - CAS# 1271022-90-2 Size:Solid 10 mg Identification and characterization of smallBMS 911543 is an orally available small molecule targeting a subset of Janus associated kinase (JAK) with potential antineoplastic activity. JAK2 inhibitor BMS 911543 selectively inhibits JAK2, thereby preventing the JAK STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. JAK2, often upregulated or