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D609 - CAS# 83373-60-8 Catalog No.:M10949-10 also known as OGT 918

SKU: 44109114361

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D609 - CAS# 83373-60-8 Catalog No.:M10949-10 also known as OGT 918D 609, also known as D 609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D 609, an inhibitor of PC PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization induced contraction. D 609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction. Product information CAS Number: 83373 60 8 Molecular Weight: 266. 46

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Description

also known as OGT 918 and NB-DNJ

I-BET762 could be dosed to the mice by oral administration at 10-30 mg/kg once per day

TAS-116 is distributed less in retina than in plasma in rats

The PKC inhibitor has no effect on vascular responses in normoglycemic and TR animals

this treatment does not actually restore the colon shortening

D609 - CAS# 83373-60-8 Catalog No.:M10949-10 also known as OGT 918D 609, also known as D 609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D 609, an inhibitor of PC PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization induced contraction. D 609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction. Product information CAS Number: 83373 60 8 Molecular Weight: 266. 46

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