LDK378 dihydrochloride - CAS# 1380575-43-8 Catalog No.:M9662-10 InChi: InChI=1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6

InChi: InChI=1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6

effectively clearing the receptor from the cell surface and selectively inhibiting intracellular signaling (IC50 0

[Epub ahead of print] PubMed PMID: 27241280

14(6):1466-75

Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands

LDK378 dihydrochloride - CAS# 1380575-43-8 Catalog No.:M9662-10 InChi: InChI=1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6Ceritinib Dihydrochloride is a potent alk inhibitor Product information CAS Number: 1380575 43 8 Molecular Weight: 631. 06 Formula: C28H38Cl3N5O3S Synonym: LDK 378 dihydrochloride LDK 378 dihydrochloride Ceritinib dihydrochloride Chemical Name: 5 chloro N2 [5 methyl 4 (piperidin 4 yl) 2 (propan 2 yloxy)phenyl] N4 [2 (propane 2 sulfonyl)phenyl]pyrimidine 2,4 diamine dihydrochloride Smiles: Cl. Cl.