AR7 - RARα antagonist. CAS# 80306-38-3 302 artholomeusz G
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AR7 - RARα antagonist. CAS# 80306-38-3 302 artholomeusz GAR7, CAS No. 80306 38 3, was developed as a highly potent and selective enhancer of the chaperone mediated autophagy (CMA) through antagonizing RAR. It is a synthetic derivative of all trans retinoic acid developed through the structure based chemical design. CMA contributes to cellular quality control and the cellular response to stress through the selective degradation of cytosolic proteins in lysosomes. A decrease in CMA activity occurs in aging
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