Cobicistat - CAS# 1004316-88-4 iin 11(8):822-6

11(8):822-6

MacLaren AP

is an approved drug for use in the treatment of infection with the human immunodeficiency virus (HIV)

a focal adhesion kinase (FAK) inhibitor in Japanese patients with advanced solid tumors

Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NC[C@H](O)CN1CCOCC1

Cobicistat - CAS# 1004316-88-4 iin 11(8):822-6Cobicistat, also known as GS9350, is an approved drug for use in the treatment of infection with the human immunodeficiency virus (HIV). Like ritonavir (Norvir), cobicistat is of interest not for its anti HIV properties, but rather its ability to inhibit liver enzymes that metabolize other medications used to treat HIV, notably elvitegravir, an HIV integrase inhibitor currently under investigation itself. By combining cobicistat with elvitegravir,