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TAS-116 - CAS# 1260533-36-5 Catalog No.:M6713-2 InChi: InChI=1S/C23H21N5O3S

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TAS-116 - CAS# 1260533-36-5 Catalog No.:M6713-2 InChi: InChI=1S/C23H21N5O3STAS 116, CAS No. 1260533 36 5, also known as Pimitespib, is a potent and selective inhibitor of heat shock protein 90 (Hsp90) subtypes alpha and beta, with potential antineoplastic and chemo radiosensitizing activities. TAS 116 specifically binds to and inhibits the activity of Hsp90 alpha and beta; this results in the proteasomal degradation of oncogenic client proteins, which inhibits client protein dependent signaling, induces apoptosis, and

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Description

InChi: InChI=1S/C23H21N5O3S

PubMed PMID: 31525930

CAS Number: 103883-03-0

and cancer

which shows a distinct mechanism of action from other AKT inhibitors

TAS-116 - CAS# 1260533-36-5 Catalog No.:M6713-2 InChi: InChI=1S/C23H21N5O3STAS 116, CAS No. 1260533 36 5, also known as Pimitespib, is a potent and selective inhibitor of heat shock protein 90 (Hsp90) subtypes alpha and beta, with potential antineoplastic and chemo radiosensitizing activities. TAS 116 specifically binds to and inhibits the activity of Hsp90 alpha and beta; this results in the proteasomal degradation of oncogenic client proteins, which inhibits client protein dependent signaling, induces apoptosis, and

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