Raltegravir (MK-0518) r Agonist InChi: InChI=1S/C33H33N3O15/c1-3-43-29(38)17-4-6-18(7-5-17)34-31(39)49-26-25(14-37)48-30(42-2)28(51-33(41)36-20-9-11-22-24(13-20)47-16-45-22)27(26)50-32(40)35-19-8-10-21-23(12-19)46-15-44-21/h4-13

InChi: InChI=1S/C33H33N3O15/c1-3-43-29(38)17-4-6-18(7-5-17)34-31(39)49-26-25(14-37)48-30(42-2)28(51-33(41)36-20-9-11-22-24(13-20)47-16-45-22)27(26)50-32(40)35-19-8-10-21-23(12-19)46-15-44-21/h4-13

217-225 (2005)

Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer

1-2H3/t18-

It incorporates an E3 ligase ligand plus a PEG5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand

Raltegravir (MK-0518) r Agonist InChi: InChI=1S/C33H33N3O15/c1-3-43-29(38)17-4-6-18(7-5-17)34-31(39)49-26-25(14-37)48-30(42-2)28(51-33(41)36-20-9-11-22-24(13-20)47-16-45-22)27(26)50-32(40)35-19-8-10-21-23(12-19)46-15-44-21/h4-13Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. Product information CAS Number: 518048 05 0 Molecular Weight: 444. 42 Formula: C20H21FN6O5 Synonym: Isentress Related CAS Number: 871038 72 1 (Raltegravir potassium) Chemical Name: N [(4 fluorophenyl)methyl] 5 hydroxy 1 methyl 2 {2 [(5 methyl 1, 3, 4 oxadiazol 2 yl)formamido]propan 2 yl} 6 oxo 1, 6 dihydropyrimidine 4 carboxamide Smiles: