VX-222 cis - CAS# 1026785-59-0 Catalog No.:M10875-2 Reduced methylene Blue dihydrobromide

SKU: 63030726197

Pay in 4 interest-free payments of $23.75 Learn more

Live Spec

VX-222 cis - CAS# 1026785-59-0 Catalog No.:M10875-2 Reduced methylene Blue dihydrobromideLomibuvir, also known as VX 222, VCH 222 and VX22, is an nonnucleoside NS5B polymerase inhibitor. VX 222 inhibits the 1b Con1 HCV subgenomic replicon, with 50% effective concentrations (EC(50)s) 5 nM. VX 222 binds to the HCV polymerase with dissociation constants of 17 nM. In phase 1 and 2 clinical studies, VX 222 demonstrated effective antiviral efficacy, with substantial reductions in plasma HCV RNA in patients chronically infected with genotype 1

Store: www.ab-travaux.com · Domain: www.ab-travaux.com