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MDL-29951 - CAS# 130798-51-5 size:10mg solid Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1=CC=C(Cl)C=C1Cl

MDL-29951 - CAS# 130798-51-5 size:10mg solid Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1=CC=C(Cl)C=C1Cl

Name: MDL-29951 - CAS# 130798-51-5 size:10mg solid Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1=CC=C(Cl)C=C1Cl
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SKU: 79534102215
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MDL-29951 - CAS# 130798-51-5 size:10mg solid Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1=CC=C(Cl)C=C1ClMDL 29951, CAS No. 130798 51 5, is a novel glycine antagonist of NMDA receptor activation, with Ki of 0. 14 M for [3H]glycine binding in vitro and in vivo. Product information CAS Number: 130798 51 5 Molecular Weight: 302. 11 Formula: C12H9Cl2NO4 Chemical Name: 2 Carboxy 4,6 dichloro 1H indole 3 propanoic acid Smiles: OC(=O)CCC1=C(NC2=CC(Cl)=CC(Cl)=C12)C(O)=O InChiKey: KNBSYZNKEAWABY UHFFFAOYSA N InChi: InChI=1S C12H9Cl2NO4 c13 5 3 7(14)10 6(1 2

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Description

Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1=CC=C(Cl)C=C1Cl

I-BET762 could be dosed to the mice by oral administration at 10-30 mg/kg once per day

interfered with autophagy

and induced cancer cell death

It inhibits HDAC1 and HDAC3 with IC50 of 0

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