OSI-930 fenadine HCl 19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14

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OSI-930 fenadine HCl 19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14OSI 930 is a selective thiophene derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI 930 inhibits stem cell factor receptor (c Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c Kit and VEGFR2 are overexpressed in a variety of cancers. Check for active clinical trials or closed

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