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$Riociguat - CAS# 625115-55-1 carbazone Smiles: CC(C)(C)[C@H](NC(=O)[C@@H](NC)C(C)(C)C1C=CC=CC=1)C(=O)N(C)[C@H](/C=C(\C)/C(O)=O)C(C)C$

Riociguat - CAS# 625115-55-1 carbazone Smiles: CC(C)(C)[C@H](NC(=O)[C@@H](NC)C(C)(C)C1C=CC=CC=1)C(=O)N(C)[C@H](/C=C(\C)/C(O)=O)C(C)C

Name: Riociguat - CAS# 625115-55-1 carbazone Smiles: CC(C)(C)[C@H](NC(=O)[C@@H](NC)C(C)(C)C1C=CC=CC=1)C(=O)N(C)[C@H](/C=C(\C)/C(O)=O)C(C)C
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Riociguat - CAS# 625115-55-1 carbazone Smiles: CC(C)(C)[C@H](NC(=O)[C@@H](NC)C(C)(C)C1C=CC=CC=1)C(=O)N(C)[C@H](/C=C(\C)/C(O)=O)C(C)CRiociguat, also known as BAY 63 2521, is a novel drug that is currently in clinical development by Bayer. It is a stimulator of soluble guanylate cyclase (sGC). At the moment Phase III clinical trials investigate the use of riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class

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Description

Smiles: CC(C)(C)[C@H](NC(=O)[C@@H](NC)C(C)(C)C1C=CC=CC=1)C(=O)N(C)[C@H](/C=C(\C)/C(O)=O)C(C)C

InChi: InChI=1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24

31(5):845-52

4R)-4-benzyl-2-hydroxy-4-{[(1S

Molecular Weight: 947

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