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OSI-906 Size:10mg solid ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23

SKU: 97796640028

4.8
USD126.00 USD152.00

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OSI-906 Size:10mg solid ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23OSI 906, is a n orally bioavailable small molecule inhibitor of the insulin like growth factor 1 receptor (IGF 1R) with potential antineoplastic activity. OSI 906 selectively inhibits IGF 1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR 1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Product

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Description

ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23

Nephrology Dialysis Transplantation

PubMed PMID: 17889719

injection to mice bearing bilateral subcutaneous xenografts Rh12 or Rh18

Romidepsin

OSI-906 Size:10mg solid ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23OSI 906, is a n orally bioavailable small molecule inhibitor of the insulin like growth factor 1 receptor (IGF 1R) with potential antineoplastic activity. OSI 906 selectively inhibits IGF 1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR 1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Product

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