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Raltitrexed - CAS# 112887-68-0 sinone 15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H

Raltitrexed - CAS# 112887-68-0 sinone 15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H

Name: Raltitrexed - CAS# 112887-68-0 sinone 15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H
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Raltitrexed - CAS# 112887-68-0 sinone 15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4HRaltitrexed, also known as ZD 1694, is an antimetabolite drug used in treatment of colorectal cancer since 1998. It may also be used in the treatment of malignant mesothelioma. It is an inhibitor of thymidylate synthase, and is manufactured by AstraZeneca. Raltitrexed is a quinazoline folate analogue with antineoplastic activity. After transport into cells via the reduced folate carrier, raltitrexed undergoes intracellular polyglutamation and blocks

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Description

15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H

Naringin suppresses NF-κB signaling pathway

and prevents α-synuclein and amyloid-β oligomerization and fibril formation

InChiKey: XBUDZAQEMFGLEU-UHFFFAOYSA-N

Kaspers GJ

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