glp-1 receptor agonists and cardiovascular outcome trials an update The Many Benefits of Drugs Meta-analysis of 11 clinical trials

Name: glp-1 receptor agonists and cardiovascular outcome trials an update The Many Benefits of Drugs Meta-analysis of 11 clinical trials
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Meta analysis of 11 clinical trials showing that GLP 1 receptor agonists significantly reduce the risk of kidney outcomes, major adverse cardiovascular events, and all cause death, without increasing the risk of serious adverse events Cardiovascular Protective Properties of GLP 1 Receptor Agonists: More than Just Diabetic and Weight Loss Drugs Beyond GLP1: modulating multiple nutrient stimulated hormone pathways to reduce cardiovascular risk Nature Reviews Cardiology Real World Evidence for GLP 1 Receptor Agonists Across the CKD Spectrum AJKD Blog GLP 1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal. GLP 1RAs reduce cardiovascular deaths in patients with CKM comorbidity Duke Clinical Research Institute posted on the topic LinkedIn

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Citation: ClinicalTrials.gov

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Gastroenterology 2019

In healthy individuals, the incretin effect stimulates insulin secretion, accounting for about 70% of total insulin secretion, with GIP contributing two-thirds of this effect, which is higher than that of GLP-1