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However, both medications produce substantial, clinically significant weight loss that far exceeds what most people achieve through diet and exercise alone

1 The additional GIP activation provides extra blood sugar control and appetite management beyond what GLP-1 alone achieves

Once you begin using a vial by drawing doses, the stability period shortens significantly because needle punctures introduce potential contamination and exposure to air

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For people who fail dual agonism, triple agonism may provide the additional stimulus needed

The reason why has to do with how the medications work in your body