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Inhibiting System Xc- leads to decreased GSH levels, reduced GPX4 activity, and weakened cellular antioxidant capacity, promoting ferroptosis (Li FJ

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Leg crampscharacterised by sudden, involuntary, and often painful muscle contractionscan have multiple causes, including dehydration, electrolyte imbalances (particularly low potassium, magnesium, or calcium), reduced caloric intake, increased physical activity, or underlying medical conditions

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George Tidmarsh, director of the FDA's Center for Drug Evaluation and Research, said