UHRF1 Monoclonal Antibody, 100ul Custom Peptide Synthesis a progressive neurologic developmental disorder

a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females

A pseudogene of AKAP8 is located on the short arm of chromosome 9

Both N- and C-terminal domains are required for transcriptional activation

transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3

A snoRNA gene (SNORD61) is found in one of its introns

UHRF1 Monoclonal Antibody, 100ul Custom Peptide Synthesis a progressive neurologic developmental disorderThis gene encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent DNA damage