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Notably, the extent of weight loss achieved with GLP-1 RA therapy may be directly linked to the degree of reduction in preference for high-calorie foods as semaglutide was associated with reduced cravings for both savory and sugary foods, with decreases in craving scores correlating with greater weight loss (Wharton et al., 2023) which persisted for up to 2 years (Wharton et al., 2023)