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DiRECT found high rates of type 2 diabetes remission among people who lost a significant amount of weight about 22 pounds and sustained the weight loss over 12 to 24 months

A report from the Framingham Offspring Study of 2,999 adults found the following average daily B12 intakes, including fortified foods and supplements (Tucker, 2000): Age 26-49: 8.9 g Age 50-64: 8.7 g Age 65-83: 8.5 g A 2015-2016 National Health and Nutrition Examination Survey of over 4,500 adults 60 years and older found the following average daily B12 intakes (USDA NHANES, 2019): Male non-supplement users (68% of men): 4.5 g Male supplement users: 5.3 g from food plus 326 g from supplements Female non-supplement users (63% of women): 3.6 g Female supplement users: 3.8 g from food plus 520 g from supplements European Food Safety Authoritys Recommendations In 2015, the EFSA released recommendations for B12 intake across Europe

Cognitive impairment was present in 12 patients (54.5%) and 8 patients (36.4%)

Slowing Gastric Emptying : GLP-1 slows the gastric emptying process, meaning it takes longer for food to leave the stomach and enter the intestines

Both supplements can be beneficial depending on the clients goals

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