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continuous treatment or maintenance sessions are necessary to uphold results

doi: 10.1016/j.jbc.2023.105046

Pyruvate/malate shuttle In pancreatic beta cells, GSIS stimulates the export of malate from mitochondria to the cytoplasm [41]

This supports a direct interaction, although their underlying mechanisms are still in the early stages of investigation and further studies with larger sample sizes or validation are required (Wang Q