IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development There are six pseudogenes of

There are six pseudogenes of this gene found on chromosomes 2

This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate

Belongs to the small leucine-rich proteoglycan (SLRP) family

Defects in this gene are a cause of several syndromes

The receptor can also function in antigen capture and presentation

IRF-3 Polyclonal Antibody, 50ul[BT-AP04627] Antibody Development There are six pseudogenes ofIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed