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2.8 Immune infiltration analysis To further explore the regulatory roles of key genes in the RA immune microenvironment, CIBERSORT was used in conjunction with the LM22 reference gene set to quantify the infiltration of 22 immune cell types, and immune cell composition was compared between RA and healthy control groups

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From a mechanistic standpoint, the ability of retatrutide to sustain benefits over many months likely reflects both its pharmacokinetic profile and its triple-agonist mechanism