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The findings demonstrated that the ALCAR group experienced statistically significant improvements in musculoskeletal pain, depressive symptoms, and overall quality of life compared to the control group, with drastic reductions in both the Fibromyalgia Impact Questionnaire (FIQ) and Patient Health Questionnaire (PHQ-9) scores

IGF-1R, 1:1000, Abcam

SSRI concentrations were assayed from plasma by Thomas B

95% CI 0.290.75)

The concentration of the FITC-dextran was determined using a fluorimeter with an excitation wavelength at 490 nm and an emission wavelength of 530 nm

Iron overload induces ferroptosis by activating Piezo1, a pressure-sensitive calcium channel in chondrocytes, leading to subsequent calcium inflow, which could be exacerbated by conditional GPX4 knockout in cartilage