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Data availability Quantitative raw data can be provided by Laurent Gautron as Prism files upon request

Jul 2017;105:186-193

GLP-1RAs mimic the effects of native GLP-1, but as the resulting pharmacological concentrations reach supraphysiological levels, GLP-1 RAs have been shown to exert pleiotropic effects beyond glucose control [6], such as stimulation of the activity of the hypothalamic-pituitary- adrenal axis [7,8,9,10]

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