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Long-term (6 months and beyond), the benefits are foundational

Higher doses of berberine may be needed in order to reduce Lp(a)[ref][ref]

The safety of this product for expectant or nursing mothers cannot be demonstrated by the available evidence

Psychiatry 26, 25622576

[2] Second, in cultured dermal microvascular and fibroblast models, GHK-Cu exposure has been associated with increased vascular endothelial growth factor expression, a change that could enhance perifollicular microcirculation