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What we do know is that topical glutathione appears to work best as part of combination therapy

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Icariside II preconditioning evokes robust neuroprotection against ischaemic stroke, by targeting Nrf2 and the OXPHOS/NF-kappaB/ferroptosis pathway

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Xiong W, Zhang L, Liu H, Li N, Du Y, He H, Zhang Z, Liu Y

PLoS One 8 , e66808 (2013)