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Per the Ozempic prescribing information, treatment begins at 0.25 mg once weekly for 4 weeks (a tolerance-building step), then increases to 0.5 mg, with further increases to 1 mg and 2 mg as needed after at least 4 weeks on each level (FDA label)

Last reviewed: June 17, 2026 Last updated: June 17, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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When patients recognize weight regain or worsening glucose control after discontinuation, they often seek guidance on safely restarting treatment

After trying everything that had always worked in the past and being unsuccessful, I decided to try Trizepitide