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Always consult your provider before starting multiple therapies

(n = 3)

Only five studies were gender matched [60, 73, 75, 83, 89], four did not provide the gender of cases or controls [50, 59, 71, 89] and nine provided the gender of cases but not controls [4648, 50, 70, 73, 79, 83, 91]

UK patients should understand that: Available evidence is largely from Phase 2 studies with relatively short follow-up periods Long-term cardiovascular outcome data are not yet available for either agent Phase 3 trials are ongoing, and results will inform future regulatory submissions to the MHRA UK patients interested in accessing these treatments through clinical trials may wish to consult the NIHR 'Be Part of Research' portal (bepartofresearch.nihr.ac.uk) or ClinicalTrials.gov for current recruitment opportunities

To date, only a limited number of studies have been conducted in this regard, and various reports have been published, as detailed below

Congratulations and looking forward for continued success in Phase 3