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Professor Holsts great scientific achievements include the discovery of GLP-1 (glucagon-like peptide 1) a gut hormone regulating insulin secretion and appetite and food intake and his subsequent both basic and translational research in this field

This extended gastric retention leads to prolonged satiety after meals and a more gradual release of nutrients into the bloodstream, helping reduce sharp post-meal glucose fluctuations

Abstract from the 83rd American Diabetes Association meeting

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Long game

Summary Obesity is a chronic progressive disease with increasing prevalence in the United States and around the world