glp-1 and osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling Retrospective study examined 48 patients

Name: glp-1 and osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling Retrospective study examined 48 patients
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Retrospective study examined 48 patients with PsA initiating GLP 1RAs. Over 1 year, 60% of patients achieved weight loss 5% initial body weight. Greater weight loss was associated with greater improvements in PsA GLP 1 Inhibitor Reduces Knee Osteoarthritis Pain RheumNow Glucagon like peptide 1 receptor regulates endoplasmic reticulum stress induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat Cell Death & Disease Two birds with one stone Semaglutide's impacts on obesity and knee osteoarthritis: From weight loss to pain relief glp 1 osteoarthritis GLP 1 Agonists and Orthopedic Surgery: A Review of Their Impact on Bone Metabolism, Wound Healing, and Surgical Outcomes GLP 1s may increase risk of Targeting the GLP 1 GLP 1R axis to treat osteoarthritis: A new opportunity? PMC

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