tirzepatide discontinuation weight regain study after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial Real-world studies of GLP-1 discontinuation
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Real world studies of GLP 1 discontinuation showed that patients often regain weight at a significantly faster pace than after other weight loss methods. At the same time, however, novel strategies aimed at countering those Tirzepatide for the Maintenance of Body Weight Reduction: Rationale, Design, and Baseline Characteristics of SURMOUNTMAINTAIN Horn 2025 Obesity Wiley Online Library Weight Regain After Liraglutide, Semaglutide or Tirzepatide Interruption: A Narrative Review of Randomized Studies Tirzepatide withdrawal leads to 25% weight regain in 82.5% of adults Diabetes Distilled: Weight regain after stopping newer weight management drugs is faster than anticipated DiabetesontheNet Tirzepatide for maintenance of bodyweight reduction in people with obesity in the USA (SURMOUNT MAINTAIN): a multicentre, double blind, randomised, placebo controlled trial The Lancet
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