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GLP-1 receptor agonists like semaglutide and tirzepatide act on incretin pathways through GLP-1 and GIP receptors, with central appetite suppression and slowed gastric emptying as primary mechanisms

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The major difference between a B12 shot and an oral supplement is that the B12 shots or injectables are directly put into the bloodstream while the oral ones take time to ingest through the bodys digestive system