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ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges miscellaneous:Knockdown significantly reduces the adhesion

SKU: 9261377334

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ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges miscellaneous:Knockdown significantly reduces the adhesionThis gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain proline rich region and Src homology 3 (SH3) domain and are components of the Abi WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21 activated kinase. Alternative splicing

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Description

miscellaneous:Knockdown significantly reduces the adhesion of cancer cells to lung microvascular endothelial cells and the reciprocal effect is observed following overexpression

EF-hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes

including Dbf4

Although three transcripts are detected in northern blots

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

ABI3 Polyclonal Antibody, 20ul Low-speed Centrifuges miscellaneous:Knockdown significantly reduces the adhesionThis gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain proline rich region and Src homology 3 (SH3) domain and are components of the Abi WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21 activated kinase. Alternative splicing

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