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The lead researcher of the study and doctors share how these side effects can interfere with exercise and how to adjust your training when taking a GLP-1 medication

Topiramate, an anticonvulsant used off-label for weight management, produces modest weight loss by reducing appetite and increasing satiety

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In fact, they hinted that if results are ready in time, they might submit retatrutide to the FDA in late 2025 , which could potentially lead to approval in 2026

Once participants reached their target dose and maintained it, GI symptoms decreased substantially