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The molecule loses biological activity through hydrolysis, oxidation, or aggregation while the solution still looks clear

Here is an example of an individual with both lesional and non-lesional KP, where lighter dotted pigmentation and erythema coexists with raised, inflamed lesions: KP is usually exclusively distributed symmetrically on the body, affecting both sides of the face, outer arms, outer thighs, buttocks, and the torso

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