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The response is mediated by a shortened cycle length and steeper diastolic depolarization potential of pacemaker action potentials and a shift of the site of earliest activation within the sinus node

Scientists at Novo Nordisk refined earlier GLP-1 medications to create a longer-acting formulation

xxv, 220 p

10.1371/journal.pone.0209681 79

Given these distinct mechanisms, cuproptosis has been implicated as a contributing factor in the pathogenesis of diverse cardiovascular diseases, including dilated cardiomyopathy, HF, and atherosclerosis [12]