MXI1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Type 1 alternative splice variants

Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIG

5)P3 and PLCG2

Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia

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MXI1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Type 1 alternative splice variantsExpression of the c myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix loop helix protein that binds to