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Blood samples for pharmacokinetic analysis were collected up to 15 min pre-dose (day 1), and at 4, 8, 12, 18, 24, 30, 36, 48, 54, 60, 72, 84, 96 and 120 h post-dose

Cuando el suministro de oxgeno al torrente sanguneo no satisface las demandas de las clulas del tejido, se produce lo que se denomina un estado de hipoxia [11]

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This happens for several reasons: Caloric deficit magnitude: The dramatic appetite suppression from semaglutide creates substantial caloric deficits