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Cdc37(Phospho Ser13) Polyclonal Antibody, 20ul Biomatrix Adrenomedullin encoded by ADM is

SKU: 33587354913

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Cdc37(Phospho Ser13) Polyclonal Antibody, 20ul Biomatrix Adrenomedullin encoded by ADM isThe protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF 1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

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Description

Adrenomedullin encoded by ADM is a preprohormone which is cleaved to form two biologically active peptides

|Involved in the activation cascade of caspases responsible for apoptosis execution

this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion

Protein kinase C alpha by PRKCA is one of the PKC family members

and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands

Cdc37(Phospho Ser13) Polyclonal Antibody, 20ul Biomatrix Adrenomedullin encoded by ADM isThe protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF 1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

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