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ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades (Block et al., 2007)

Additionally, selenium plays a role in the regulation of the immune system, such as decreasing inflammation and oxidative stress

Military-funded These findings suggest that expired medications are still generally safe to use with some exceptions

This index serves as a valuable resource for urban planners and policymakers, enabling them to prioritize inclusive project interventionsfrom environmental to socio-economicand allocate resources more effectively

For severe symptoms, like high fevers and intense pain, I often give doses one hour apart

Supplementary Information The online version contains supplementary material available at 10.1186/s13287-025-04623-9