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DOI: Published online: July 24, 2025 1 Institute of Medical Research, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea Correspondence to Seok-Woo Hong, PhD Institute of Medical Research, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Korea Email: [email protected] Won-Young Lee, MD Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Korea Email: [email protected] *Jinmi Lee and Eun-Jung Rhee contributed equally to this work as co-first authors

Statista, State of Health

The analysis identified 19 significant NAE signals associated with GLP-1 RAs, representing 11.58% of all reported AEs associated with these agents between 2005 Q2 and 2024 Q3

This can lead to potentially not getting enough nutrients like zinc, protein, iron, or calories, which can also trigger hair change

Beyond weight management, GLP-1 agonists play a role in improving insulin sensitivity and addressing metabolic issues, both of which are common concerns for women with PCOS

A 2025 Kinsey Institute survey revealed that more than half of GLP-1 users said the drugs had changed their sex and dating livessometimes for the worse